Bellen Lab

Mengqi Ma

Mengqi Ma

BS, Tongji University, China
PhD, Tsinghua University, China (Jose Carlos Pastor-Pareja)

Research Interests

Early onset rare diseases may be a more severe manifestation of neurodegenerative disorders in advance. I am interested in identifying genes involved in undiagnosed rare diseases using Drosophila as a model. I hope to take advantage of this simplified but sophisticated system to look into conserved mechanisms, so as to help understanding and therapy of the diseases.


Publications

Ma M*, Moulton MJ*, Lu S, Bellen HJ (2022) 'Fly-ing' from rare to common neurodegenerative disease mechanisms. Trends in Genetics :DOI: 10.1016/j.tig.2022.03.018. *contributed equally [Abstract]
Huang Y, Ma M, Mao X, Pehlivan D, Kanca O, Un-Candan F, Shu L, Akay G, Mitani T, Lu S, Candan S, Wang H, Xiao B, Lupski JR, Bellen HJ (2022) Novel dominant and recessive variants in human ROBO1 cause distinct neurodevelopmental defects through different mechanisms. Human Molecular Genetics :doi: 10.1093/hmg/ddac070.  [Abstract]
Dai J, Estrada B, Jacobs S, Sánchez-Sánchez BJ, Tang J, Ma M, Magadán-Corpas P, Pastor-Pareja JC, Martín-Bermudo MD (2018) Dissection of Nidogen function in Drosophila reveals tissue-specific mechanisms of basement membrane assembly . PLoS Genetics 14:e1007483.  [Abstract]
Ke H, Feng Z, Liu M, Sun T, Dai J, Ma M, Liu LP, Ni JQ, Pastor-Pareja JC (2018) Collagen secretion screening in Drosophila supports a common secretory machinery and multiple Rab requirements. Journal of Genetics and Genomics 45:299-313.  [Abstract]
Dai J, Ma M, Feng Z, Pastor-Pareja JC (2017) Inter-adipocyte adhesion and signaling by Collagen IV intercellular concentrations in Drosophila. Current Biology 27:2729-2740.  [Abstract]
Ma M, Cao X, Dai J, Pastor-Pareja JC (2017) Basement membrane manipulation in Drosophila wing discs affects Dpp retention but not growth mechanoregulation. Developmental Cell 42:97-106.  [Abstract]

Last Modified 07-22-2022 by Zhongyuan Zuo

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